Reigning champions Vipers SC host debutants Ntugasaze FC at St Mary's Stadium on Thursday as both sides hunt their first points of the StarTimes Uganda Premier League 2026/27 season.
The Venoms fell 1-0 to Entebbe UPPC in their opener while the Brewers remain winless after three matches played.
Denis Lavagne's men saw their continental campaign end at the preliminary round against Mauritania's Nouadhibou and attention now shifts fully to league defence.
The French tactician faces selection headaches up front where Ceaser Lobi Manzoki and Gusto Mulongo compete for the starting berth.
Midfield options are equally stacked with Joel Sserunjogi, Marvin Youngman, Karim Watambala and Farouk Miya all pushing for places.
This will be the first ever official meeting between the two outfits and the fixture concludes match day four before the international break.
Match day four fixtures and results
- Vipers SC vs Ntugasaze FC
- Other fixtures to follow
Source: Uganda Premier League